대한의사협회지 2012;55:381
B. Precautions: General
1. Loading doses require no renal dose adjustment
2. For patients on renal replacement
1. Dialyzed medications should be taken after Hemodialysis run for the day
2. Peritoneal Dialysis does not affect the timing of medications
3. For patients on Phosphate Binders
1. Take medications (esp. antibiotics) one hour before or 3 hours after Phosphate Binder dose
4. Maintenance doses can be adjusted in 2 ways
1. Reduce each dose, but maintain same dose interval
1. Risks toxicity due to drug accumulation
2. Maintain same dose, but lengthen dosing interval
1. Risks sub-therapeutic dosing
