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F3. NEONATAL SEIZURES

(1) / 신경학적 발달이 이뤄지지 않아서 리스크 높으며 예후도 불량 적극적인 평가가 요구됨 (2) Birth and maternal history (e.g., with group B streptococci or herpes simplex virus) & Withdrawal from maternal narcotics (3) Neonates with witnessed seizures require extensive evaluation & admission to the hospital ① Evaluation culture (blood, urine, CSF) ② Test for herpes simplex virus ③ Begin empiric parenteral IV antibiotics & Acyclovir (4) Toxicologic evaluation & Withdrawal or overdose of abused substances (5) Electrolyte abnormalities than older children (Ca, glucose !) 측정 (6) Head CT evaluates (7) Inborn errors of metabolism 의심되면 → Lactate, Ammonia, Serum amino acids, Urine organic acids level (8) Treat the actively seizing neonate with benzodiazepines as with older children ① Consider phenobarbital for second-line therapy because many will be sent home on phenobarbital. (Neonate<1month : phenobarbital !!)