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3개월 이상 지속 시
1.
관련인자
(1) Older age (2) Allergic rhinitis (3) Recurrent viral URIs
(4) Immunodeficiency (5) Ciliary dyskinesia (6) Anatomic abnormalities
(7) Fungal colonization
2.
Pathogen
(1) M/C : α-hemolytic Streptococcus, H. influenzae, and S. pneumoniae
(2) Staphylococcus aureus, anaerobes, fungi (rare)
3.
Treatments
(1) Cover aerobic and anaerobic β-lactamase–producing bacteria
(2) Amoxicillin-clavulanate, clindamycin, quinolones
(3) At least 4 weeks
(4) Surgery : functional endoscopic sinus surgery
